Genetic and Structural Implications of Tryptic Peptide Analysis of Poliovirus Structural Protein
نویسندگان
چکیده
منابع مشابه
Structural and genetic analysis of protein stability.
One very encouraging development has been the freedom with which amino acid replacements can be introduced in a protein of interest. This has made it possible to obtain detailed structural and thermodynamic data on a wide variety of mutants that modify protein stability. Substitutions of solvent-exposed amino acids on the surfaces of proteins are seen to have little if any effect on protein sta...
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Analysis of [35S]methionine-labeled tryptic peptides of the large proteins induced by temperature-sensitive mutants of Semliki Forest virus was carried out. The 130,000-molecular-weight protein induced by ts-2 and ts-3 mutants contained the peptides of capsid protein and of both major envelope proteins E1 and E2. The ts-3-induced protein with molecular weight of 97,000 contained peptides of the...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1973
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-20-2-151